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Involvement of HECTD1 in LPS-induced astrocyte activation via σ-1R-JNK/p38-FOXJ2 axis

BACKGROUND: Astrocytes participate in innate inflammatory responses within the mammalian central nervous system (CNS). HECT domain E3 ubiquitin protein ligase 1 (HECTD1) functions during microglial activation, suggesting a connection with neuroinflammation. However, the potential role of HECTD1 in a...

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Detalles Bibliográficos
Autores principales:	Tang, Ying, Zhou, Mengchun, Huang, Rongrong, Shen, Ling, Yang, Li, Zhou, Zhongqiu, Ren, Hui, Bai, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008527/ https://www.ncbi.nlm.nih.gov/pubmed/33781347 http://dx.doi.org/10.1186/s13578-021-00572-x

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