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Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine learning toolbox

The human microbiome is increasingly mined for diagnostic and therapeutic biomarkers using machine learning (ML). However, metagenomics-specific software is scarce, and overoptimistic evaluation and limited cross-study generalization are prevailing issues. To address these, we developed SIAMCAT, a v...

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Detalles Bibliográficos
Autores principales: Wirbel, Jakob, Zych, Konrad, Essex, Morgan, Karcher, Nicolai, Kartal, Ece, Salazar, Guillem, Bork, Peer, Sunagawa, Shinichi, Zeller, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008609/
https://www.ncbi.nlm.nih.gov/pubmed/33785070
http://dx.doi.org/10.1186/s13059-021-02306-1