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Acacetin ameliorates insulin resistance in obesity mice through regulating Treg/Th17 balance via MiR-23b-3p/NEU1 Axis

BACKGROUND: The role of miR-23b-3p in insulin resistance (IR) remained poorly understood. METHODS: After acacetin injection, obesity-induced IR model was constructed with or without miR-23b-3p upregulation and Neuraminidase 1 (NEU1) overexpression in mice. Body weight, serum metabolite and fat perce...

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Detalles Bibliográficos
Autores principales: Wei, Yan, Jing, Jianhong, Peng, Zhiping, Liu, Xiaoqian, Wang, Xueyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008644/
https://www.ncbi.nlm.nih.gov/pubmed/33781239
http://dx.doi.org/10.1186/s12902-021-00688-8