Muscle atrophy induced by overexpression of ALAS2 is related to muscle mitochondrial dysfunction

BACKGROUND: ALAS2 (delta-aminolevulinate synthase 2) is one of the two isoenzymes catalyzing the synthesis of delta-aminolevulinic acid (ALA), which is the first precursor of heme synthesis. ALAS2-overexpressing transgenic mice (Tg mice) showed syndrome of porphyria, a series of diseases related to...

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Detalles Bibliográficos
Autores principales: Peng, Yahui, Li, Jihong, Luo, Dixian, Zhang, Shuai, Li, Sijia, Wang, Dayong, Wang, Xidi, Zhang, Zhujun, Wang, Xue, Sun, Changhui, Gao, Xu, Hui, Yang, He, Rongzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008657/
https://www.ncbi.nlm.nih.gov/pubmed/33785075
http://dx.doi.org/10.1186/s13395-021-00263-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008657/
https://www.ncbi.nlm.nih.gov/pubmed/33785075
http://dx.doi.org/10.1186/s13395-021-00263-8

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