Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil

INTRODUCTION: Leprosy recurrence is the reappearance of the disease after treatment with current schemes and discharged for cure and may have variable incubation periods. METHODS: This is a descriptive observational study of leprosy recurrence in Espírito Santo diagnosed between January 2018 and Jan...

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Autores principales: Chagas, Danielle Ferreira, Diniz, Lucia Martins, Lucas, Elton Almeida, de Moraes, Milton Ozório
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008889/
https://www.ncbi.nlm.nih.gov/pubmed/33681915
http://dx.doi.org/10.1590/0037-8682-0375-2020
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author Chagas, Danielle Ferreira
Diniz, Lucia Martins
Lucas, Elton Almeida
de Moraes, Milton Ozório
author_facet Chagas, Danielle Ferreira
Diniz, Lucia Martins
Lucas, Elton Almeida
de Moraes, Milton Ozório
author_sort Chagas, Danielle Ferreira
collection PubMed
description INTRODUCTION: Leprosy recurrence is the reappearance of the disease after treatment with current schemes and discharged for cure and may have variable incubation periods. METHODS: This is a descriptive observational study of leprosy recurrence in Espírito Santo diagnosed between January 2018 and January 2020. RESULTS: One hundred and ninety-two cases were available, of which 30 were diagnosed with leprosy recurrence. CONCLUSIONS: In 25 cases, the incubation period was 5-15 years after the first treatment, favoring bacillary persistence. In the remaining 5 cases, the disease had recurred after 15 years, pointing to reinfection as none of them exhibited drug resistance.
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spelling pubmed-80088892021-04-01 Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil Chagas, Danielle Ferreira Diniz, Lucia Martins Lucas, Elton Almeida de Moraes, Milton Ozório Rev Soc Bras Med Trop Short Communication INTRODUCTION: Leprosy recurrence is the reappearance of the disease after treatment with current schemes and discharged for cure and may have variable incubation periods. METHODS: This is a descriptive observational study of leprosy recurrence in Espírito Santo diagnosed between January 2018 and January 2020. RESULTS: One hundred and ninety-two cases were available, of which 30 were diagnosed with leprosy recurrence. CONCLUSIONS: In 25 cases, the incubation period was 5-15 years after the first treatment, favoring bacillary persistence. In the remaining 5 cases, the disease had recurred after 15 years, pointing to reinfection as none of them exhibited drug resistance. Sociedade Brasileira de Medicina Tropical - SBMT 2021-03-08 /pmc/articles/PMC8008889/ /pubmed/33681915 http://dx.doi.org/10.1590/0037-8682-0375-2020 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Short Communication
Chagas, Danielle Ferreira
Diniz, Lucia Martins
Lucas, Elton Almeida
de Moraes, Milton Ozório
Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
title Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
title_full Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
title_fullStr Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
title_full_unstemmed Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
title_short Relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of Espírito Santo, Brazil
title_sort relapse in leprosy and drug resistance assessment in a tertiary hospital of the state of espírito santo, brazil
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008889/
https://www.ncbi.nlm.nih.gov/pubmed/33681915
http://dx.doi.org/10.1590/0037-8682-0375-2020
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