First report of bla (GES-1) in Proteus mirabilis clinical isolates

Proteus mirabilis is one of the main pathogens causing urinary tract infections and sepsis. To our knowledge, this is the first report of a P. mirabilis hosting bla (GES). The presence of these genes was determined using PCR and sequencing. We identified the presence of bla (GES-1) in all three isol...

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Detalles Bibliográficos
Autores principales: Beltrão, Elizabeth Maria Bispo, de Oliveira, Érica Maria, Lopes, Ana Catarina de Souza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008897/
https://www.ncbi.nlm.nih.gov/pubmed/33759932
http://dx.doi.org/10.1590/0037-8682-0864-2020
Descripción
Sumario:Proteus mirabilis is one of the main pathogens causing urinary tract infections and sepsis. To our knowledge, this is the first report of a P. mirabilis hosting bla (GES). The presence of these genes was determined using PCR and sequencing. We identified the presence of bla (GES-1) in all three isolates. In addition, we identified the bla (KPC-2) and bla (NDM-1) genes in the two strains. These data emphasize the importance of monitoring and surveillance of all enterobacteria. The circulation of P. mirabilis strains carrying bla (GES-1) constitutes a new scenario of resistance in this species and should be an epidemiological alert for global health.

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