First report of bla (GES-1) in Proteus mirabilis clinical isolates

Proteus mirabilis is one of the main pathogens causing urinary tract infections and sepsis. To our knowledge, this is the first report of a P. mirabilis hosting bla (GES). The presence of these genes was determined using PCR and sequencing. We identified the presence of bla (GES-1) in all three isol...

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Autores principales: Beltrão, Elizabeth Maria Bispo, de Oliveira, Érica Maria, Lopes, Ana Catarina de Souza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008897/
https://www.ncbi.nlm.nih.gov/pubmed/33759932
http://dx.doi.org/10.1590/0037-8682-0864-2020
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author Beltrão, Elizabeth Maria Bispo
de Oliveira, Érica Maria
Lopes, Ana Catarina de Souza
author_facet Beltrão, Elizabeth Maria Bispo
de Oliveira, Érica Maria
Lopes, Ana Catarina de Souza
author_sort Beltrão, Elizabeth Maria Bispo
collection PubMed
description Proteus mirabilis is one of the main pathogens causing urinary tract infections and sepsis. To our knowledge, this is the first report of a P. mirabilis hosting bla (GES). The presence of these genes was determined using PCR and sequencing. We identified the presence of bla (GES-1) in all three isolates. In addition, we identified the bla (KPC-2) and bla (NDM-1) genes in the two strains. These data emphasize the importance of monitoring and surveillance of all enterobacteria. The circulation of P. mirabilis strains carrying bla (GES-1) constitutes a new scenario of resistance in this species and should be an epidemiological alert for global health.
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spelling pubmed-80088972021-04-01 First report of bla (GES-1) in Proteus mirabilis clinical isolates Beltrão, Elizabeth Maria Bispo de Oliveira, Érica Maria Lopes, Ana Catarina de Souza Rev Soc Bras Med Trop Case Report Proteus mirabilis is one of the main pathogens causing urinary tract infections and sepsis. To our knowledge, this is the first report of a P. mirabilis hosting bla (GES). The presence of these genes was determined using PCR and sequencing. We identified the presence of bla (GES-1) in all three isolates. In addition, we identified the bla (KPC-2) and bla (NDM-1) genes in the two strains. These data emphasize the importance of monitoring and surveillance of all enterobacteria. The circulation of P. mirabilis strains carrying bla (GES-1) constitutes a new scenario of resistance in this species and should be an epidemiological alert for global health. Sociedade Brasileira de Medicina Tropical - SBMT 2021-03-22 /pmc/articles/PMC8008897/ /pubmed/33759932 http://dx.doi.org/10.1590/0037-8682-0864-2020 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Case Report
Beltrão, Elizabeth Maria Bispo
de Oliveira, Érica Maria
Lopes, Ana Catarina de Souza
First report of bla (GES-1) in Proteus mirabilis clinical isolates
title First report of bla (GES-1) in Proteus mirabilis clinical isolates
title_full First report of bla (GES-1) in Proteus mirabilis clinical isolates
title_fullStr First report of bla (GES-1) in Proteus mirabilis clinical isolates
title_full_unstemmed First report of bla (GES-1) in Proteus mirabilis clinical isolates
title_short First report of bla (GES-1) in Proteus mirabilis clinical isolates
title_sort first report of bla (ges-1) in proteus mirabilis clinical isolates
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008897/
https://www.ncbi.nlm.nih.gov/pubmed/33759932
http://dx.doi.org/10.1590/0037-8682-0864-2020
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