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Knockdown of Chitinase 3-Like-1 Inhibits Cell Proliferation, Promotes Apoptosis, and Enhances Effect of Anti-Programmed Death Ligand 1 (PD-L1) in Diffuse Large B Cell Lymphoma Cells

BACKGROUND: Enzymatically inactive chitinase-like protein CHI3L1 is overexpressed in diffuse large B cell lymphoma (DLBCL) patients with PD-L1 imbalance and promotes tumor progression in the microenvironment. Based on this, we investigated how CHI3L1 acts on the proliferation and apoptosis of DLBCL...

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Detalles Bibliográficos
Autores principales:	Yang, Xiao, Fang, Dong, Li, Ming, Chen, Jiayi, Cheng, Yuanbo, Luo, Jianming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2021
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008972/ https://www.ncbi.nlm.nih.gov/pubmed/33764958 http://dx.doi.org/10.12659/MSM.929431

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