Cargando…
Deep neural networks identify sequence context features predictive of transcription factor binding
Transcription factors (TFs) bind DNA by recognizing specific sequence motifs, typically of length 6–12bp. A motif can occur many thousands of times in the human genome, but only a subset of those sites are actually bound. Here we present a machine learning framework leveraging existing convolutional...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009085/ https://www.ncbi.nlm.nih.gov/pubmed/33796819 http://dx.doi.org/10.1038/s42256-020-00282-y |