Cargando…

Synergistic Inhibition of SARS-CoV-2 Replication Using Disulfiram/Ebselen and Remdesivir

[Image: see text] The SARS-CoV-2 replication and transcription complex (RTC) comprising nonstructural protein (nsp) 2–16 plays crucial roles in viral replication, reducing the efficacy of broad-spectrum nucleoside analog drugs such as remdesivir and evading innate immune responses. Most studies targ...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Ting, Fei, Cheng-Yin, Chen, Yi-Ping, Sargsyan, Karen, Chang, Chun-Ping, Yuan, Hanna S., Lim, Carmay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009100/
https://www.ncbi.nlm.nih.gov/pubmed/33855277
http://dx.doi.org/10.1021/acsptsci.1c00022