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Synergistic Inhibition of SARS-CoV-2 Replication Using Disulfiram/Ebselen and Remdesivir
[Image: see text] The SARS-CoV-2 replication and transcription complex (RTC) comprising nonstructural protein (nsp) 2–16 plays crucial roles in viral replication, reducing the efficacy of broad-spectrum nucleoside analog drugs such as remdesivir and evading innate immune responses. Most studies targ...
Autores principales: | Chen, Ting, Fei, Cheng-Yin, Chen, Yi-Ping, Sargsyan, Karen, Chang, Chun-Ping, Yuan, Hanna S., Lim, Carmay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009100/ https://www.ncbi.nlm.nih.gov/pubmed/33855277 http://dx.doi.org/10.1021/acsptsci.1c00022 |
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