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The genotype‐phenotype landscape of an allosteric protein
Allostery is a fundamental biophysical mechanism that underlies cellular sensing, signaling, and metabolism. Yet a quantitative understanding of allosteric genotype‐phenotype relationships remains elusive. Here, we report the large‐scale measurement of the genotype‐phenotype landscape for an alloste...
Autores principales: | Tack, Drew S, Tonner, Peter D, Pressman, Abe, Olson, Nathan D, Levy, Sasha F, Romantseva, Eugenia F, Alperovich, Nina, Vasilyeva, Olga, Ross, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009258/ https://www.ncbi.nlm.nih.gov/pubmed/33784029 http://dx.doi.org/10.15252/msb.202010179 |
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