The genotype‐phenotype landscape of an allosteric protein

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Allostery is a fundamental biophysical mechanism that underlies cellular sensing, signaling, and metabolism. Yet a quantitative understanding of allosteric genotype‐phenotype relationships remains elusive. Here, we report the large‐scale measurement of the genotype‐phenotype landscape for an alloste...

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Detalles Bibliográficos
Autores principales: Tack, Drew S, Tonner, Peter D, Pressman, Abe, Olson, Nathan D, Levy, Sasha F, Romantseva, Eugenia F, Alperovich, Nina, Vasilyeva, Olga, Ross, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009258/
https://www.ncbi.nlm.nih.gov/pubmed/33784029
http://dx.doi.org/10.15252/msb.202010179
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