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Natural product scaffolds as inspiration for the design and synthesis of 20S human proteasome inhibitors
The 20S proteasome is a valuable target for the treatment of a number of diseases including cancer, neurodegenerative disease, and parasitic infection. In an effort to discover novel inhibitors of the 20S proteasome, many reseaarchers have looked to natural products as potential leads for drug disco...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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RSC
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009326/ https://www.ncbi.nlm.nih.gov/pubmed/33791679 http://dx.doi.org/10.1039/d0cb00111b |