Cargando…
Phosphatidic acid-mediated binding and mammalian cell internalization of the Vibrio cholerae cytotoxin MakA
Vibrio cholerae is a noninvasive intestinal pathogen extensively studied as the causative agent of the human disease cholera. Our recent work identified MakA as a potent virulence factor of V. cholerae in both Caenorhabditis elegans and zebrafish, prompting us to investigate the potential contributi...
Autores principales: | Nadeem, Aftab, Alam, Athar, Toh, Eric, Myint, Si Lhyam, ur Rehman, Zia, Liu, Tao, Bally, Marta, Arnqvist, Anna, Wang, Hui, Zhu, Jun, Persson, Karina, Uhlin, Bernt Eric, Wai, Sun Nyunt |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009392/ https://www.ncbi.nlm.nih.gov/pubmed/33735319 http://dx.doi.org/10.1371/journal.ppat.1009414 |
Ejemplares similares
-
Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae
por: Nadeem, Aftab, et al.
Publicado: (2022) -
Bacterial protein MakA causes suppression of tumour cell proliferation via inhibition of PIP5K1α/Akt signalling
por: Toh, Eric, et al.
Publicado: (2022) -
A tripartite cytolytic toxin formed by Vibrio cholerae proteins with flagellum-facilitated secretion
por: Nadeem, Aftab, et al.
Publicado: (2021) -
Flagella-mediated secretion of a novel Vibrio cholerae cytotoxin affecting both vertebrate and invertebrate hosts
por: Dongre, Mitesh, et al.
Publicado: (2018) -
V. cholerae MakA is a cholesterol-binding pore-forming toxin that induces non-canonical autophagy
por: Jia, Xiaotong, et al.
Publicado: (2022)