POT1 stability and binding measured by fluorescence thermal shift assays

The protein POT1 (Protection of Telomeres 1) is an integral part of the shelterin complex that protects the ends of human chromosomes from degradation or end fusions. It is the only component of shelterin that binds single-stranded DNA. We describe here the application of two separate fluorescent th...

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Detalles Bibliográficos
Autores principales: DeLeeuw, Lynn W., Monsen, Robert C., Petrauskas, Vytautas, Gray, Robert D., Baranauskiene, Lina, Matulis, Daumantas, Trent, John O., Chaires, Jonathan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009405/
https://www.ncbi.nlm.nih.gov/pubmed/33784306
http://dx.doi.org/10.1371/journal.pone.0245675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009405/
https://www.ncbi.nlm.nih.gov/pubmed/33784306
http://dx.doi.org/10.1371/journal.pone.0245675

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