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Computational Analysis of Enantioselective Pd-Catalyzed α-Arylation of Ketones
[Image: see text] The direct α-arylation of carbonyl compounds emerged over the last two decades as a straightforward method for the formation of C(sp(3))–C(sp(2)) bonds. Mechanistic studies suggested a classical cross-coupling catalytic cycle. This consists of oxidative addition of the aryl halide...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009508/ https://www.ncbi.nlm.nih.gov/pubmed/32786644 http://dx.doi.org/10.1021/acs.joc.0c01768 |