ent-Beyerane Diterpenes as a Key Platform for the Development of ArnT-Mediated Colistin Resistance Inhibitors

[Image: see text] Colistin is a last-resort antibiotic for the treatment of multidrug resistant Gram-negative bacterial infections. Recently, a natural ent-beyerene diterpene was identified as a promising inhibitor of the enzyme responsible for colistin resistance mediated by lipid A aminoarabinosyl...

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Detalles Bibliográficos
Autores principales: Quaglio, Deborah, Mangoni, Maria Luisa, Stefanelli, Roberta, Corradi, Silvia, Casciaro, Bruno, Vergine, Valeria, Lucantoni, Federica, Cavinato, Luca, Cammarone, Silvia, Loffredo, Maria Rosa, Cappiello, Floriana, Calcaterra, Andrea, Erazo, Silvia, Ghirga, Francesca, Mori, Mattia, Imperi, Francesco, Ascenzioni, Fiorentina, Botta, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009527/
https://www.ncbi.nlm.nih.gov/pubmed/32806095
http://dx.doi.org/10.1021/acs.joc.0c01459

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