Cargando…

Inhibitory Effects of Periplocin on Lymphoma Cells: A Network Pharmacology Approach and Experimental Validation

PURPOSE: Lymphoma is considered to be one of the most pressing health problems worldwide owing to its high incidence and mortality. Previous studies have shown that periplocin, a naturally occurring compound, inhibits growth and induces apoptosis in several cancers. However, the effects of periploci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Riyang, Han, Chen, Dai, Suli, Wei, Sisi, Xiang, Xiaohan, Wang, Yaojie, Zhao, Ruinian, Zhao, Lianmei, Shan, Baoen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009539/ https://www.ncbi.nlm.nih.gov/pubmed/33814899 http://dx.doi.org/10.2147/DDDT.S302221

Ejemplares similares

Combination of the natural compound Periplocin and TRAIL induce esophageal squamous cell carcinoma apoptosis in vitro and in vivo: Implication in anticancer therapy
por: Han, Lujuan, et al.
Publicado: (2019)

LncRNA NR038975, A Serum-Based Biomarker, Promotes Gastric Tumorigenesis by Interacting With NF90/NF45 Complex
por: Wei, Sisi, et al.
Publicado: (2021)

MicroRNA-485-5p suppresses the progression of esophageal squamous cell carcinoma by targeting flotillin-1 and inhibits the epithelial-mesenchymal transition
por: Zhao, Riyang, et al.
Publicado: (2021)

lncRNA SNHG5 Modulates Endometrial Cancer Progression via the miR-25-3p/BTG2 Axis
por: Li, Shi, et al.
Publicado: (2019)

LncRNA SNHG5 Suppresses Cell Migration and Invasion of Human Lung Adenocarcinoma via Regulation of Epithelial-Mesenchymal Transition
por: Li, Zhirong, et al.
Publicado: (2023)

Outer Membrane Vesicles Secreted by Helicobacter pylori Transmitting Gastric Pathogenic Virulence Factors
por: Wei, Sisi, et al.
Publicado: (2021)

ESM1 Is a Promising Therapeutic Target and Prognostic Indicator for Esophageal Carcinogenesis/Esophageal Squamous Cell Carcinoma
por: Li, Juan, et al.
Publicado: (2022)

The clinical significance of Mda-7/IL-24 and C-myb expression in tumor tissues of patients with diffuse large B cell lymphoma
por: Ma, Ming, et al.
Publicado: (2018)

The NR_109/FUBP1/c-Myc axis regulates TAM polarization and remodels the tumor microenvironment to promote cancer development
por: Zhang, Cong, et al.
Publicado: (2023)

Periplocin and cardiac glycosides suppress the unfolded protein response
por: Tokugawa, Muneshige, et al.
Publicado: (2021)

LncRNA CCAT1 facilitates the progression of gastric cancer via PTBP1-mediated glycolysis enhancement
por: Zhang, Cong, et al.
Publicado: (2023)

Antitumor Effect of Periplocin in TRAIL-Resistant Human Hepatocellular Carcinoma Cells through Downregulation of IAPs
por: Cheng, Chieh-Fang, et al.
Publicado: (2013)

Periplocin inhibits the growth of pancreatic cancer by inducing apoptosis via AMPK‐mTOR signaling
por: Xie, Gangyin, et al.
Publicado: (2020)

Periplocin Induces Apoptosis of Pancreatic Cancer Cells through Autophagy via the AMPK/mTOR Pathway
por: Zhang, Hewei, et al.
Publicado: (2022)

Periplocin Overcomes Bortezomib Resistance by Suppressing the Growth and Down-Regulation of Cell Adhesion Molecules in Multiple Myeloma
por: Aziz, Abdul, et al.
Publicado: (2023)

B7‐H4 facilitates proliferation of esophageal squamous cell carcinoma cells through promoting interleukin‐6/signal transducer and activator of transcription 3 pathway activation
por: Chen, Xinran, et al.
Publicado: (2016)

Prognosis value of IL-6, IL-8, and IL-1β in serum of patients with lung cancer: A fresh look at interleukins as a biomarker
por: Yan, Xi, et al.
Publicado: (2022)

Extracellular vesicles isolated by size-exclusion chromatography present suitability for RNomics analysis in plasma
por: Yang, Yang, et al.
Publicado: (2021)

ARHI is a novel epigenetic silenced tumor suppressor in sporadic pheochromocytoma
por: Wang, Dong, et al.
Publicado: (2017)

P-glycoprotein- and organic anion-transporting polypeptide-mediated transport of periplocin may lead to drug–herb/drug–drug interactions
por: Liang, Sheng, et al.
Publicado: (2014)

Inhibitory Effects of Rabdosia rubescens in Esophageal Squamous Cell Carcinoma: Network Pharmacology and Experimental Validation
por: Lin, Ruoyang, et al.
Publicado: (2022)

Ethanol extract of Forsythia suspensa root induces apoptosis of esophageal carcinoma cells via the mitochondrial apoptotic pathway
por: ZHAO, LIANMEI, et al.
Publicado: (2015)

Higher expression level of tyrosine kinase-like orphan receptor 2 and Wnt member 5a in papillary thyroid carcinoma is associated with poor prognosis
por: Chen, Liang, et al.
Publicado: (2017)

Molecular Mechanism of Epimedium Extract against Ischemic Stroke Based on Network Pharmacology and Experimental Validation
por: Xu, Hongbei, et al.
Publicado: (2022)

Regulatory Mechanism and Experimental Verification of Patchouli Alcohol on Gastric Cancer Cell Based on Network Pharmacology
por: Song, Yanru, et al.
Publicado: (2021)

Interferon-stimulated gene 15 promotes progression of endometrial carcinoma and weakens antitumor immune response
por: Zhao, Xiwa, et al.
Publicado: (2022)

Postoperative recurrence of epithelial ovarian cancer patients and chemoresistance related protein analyses
por: Zhang, Zhengmao, et al.
Publicado: (2019)

Pharmacological Mechanism of Shen Huang Chong Ji for Treating Alzheimer's Disease Based on Network Pharmacology and Experimental Validation
por: Tang, Lei, et al.
Publicado: (2022)

Utilizing network pharmacology and experimental validation to investigate the underlying mechanism of phellodendrine on inflammation
por: Hu, Lili, et al.
Publicado: (2022)

Network pharmacology and experimental validation to identify the potential mechanism of Hedyotis diffusa Willd against rheumatoid arthritis
por: Deng, Hui, et al.
Publicado: (2023)

Deciphering the pharmacological mechanisms of Chaenomeles Fructus against rheumatoid arthritis by integrating network pharmacology and experimental validation
por: Sun, Mengjia, et al.
Publicado: (2022)

Chaihu Shugan powder alleviates liver inflammation and hepatic steatosis in NAFLD mice: A network pharmacology study and in vivo experimental validation
por: Lei, Sisi, et al.
Publicado: (2022)

Uncovering potential genes in colorectal cancer based on integrated and DNA methylation analysis in the gene expression omnibus database
por: Wang, Guanglin, et al.
Publicado: (2022)

Flotillin1 promotes EMT of human small cell lung cancer via TGF-β signaling pathway
por: Zhao, Lianmei, et al.
Publicado: (2018)

Postoperative Ileus with the Topical Application of Tongfu Decoction Based on Network Pharmacology and Experimental Validation
por: Zuo, Ximeng, et al.
Publicado: (2022)

Therapeutic Targets of Bufalin on Renal Carcinoma and Mechanisms: Experimental Validation of Network Pharmacology Analysis
por: Zhang, Lei, et al.
Publicado: (2022)

Integrating network pharmacology and experimental validation to explore the effect and mechanism of AD-1 in the treatment of colorectal cancer
por: Li, Jiawei, et al.
Publicado: (2023)

Danggui Buxue Decoction in the Treatment of Metastatic Colon Cancer: Network Pharmacology Analysis and Experimental Validation
por: Feng, Shi-Han, et al.
Publicado: (2021)

Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation
por: Shi, Lu, et al.
Publicado: (2022)

Network pharmacology combined with molecular docking and experimental validation to reveal the pharmacological mechanism of naringin against renal fibrosis
por: Zhong, Yanan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_rrc6rru3ng77bbcah3pka7m21o