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MicroRNA-138-5p Regulates Hippocampal Neuroinflammation and Cognitive Impairment by NLRP3/Caspase-1 Signaling Pathway in Rats

PURPOSE: Neuroinflammation is an essential causative factor in the pathogenesis and progression of cognitive impairment. The present study aims to evaluate the critical role of microRNA-138-5p (miR-138-5p) in hippocampal neuroinflammation and cognitive impairment through the NLRP3/caspase-1 signalin...

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Detalles Bibliográficos
Autores principales: Feng, Xiaojin, Hu, Jialing, Zhan, Fenfang, Luo, Deqiang, Hua, Fuzhou, Xu, Guohai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009546/
https://www.ncbi.nlm.nih.gov/pubmed/33814920
http://dx.doi.org/10.2147/JIR.S304461