Cargando…

EGFR Targeted Cetuximab-Valine-Citrulline (vc)-Doxorubicin Immunoconjugates- Loaded Bovine Serum Albumin (BSA) Nanoparticles for Colorectal Tumor Therapy

BACKGROUND: Specific modifications to carriers to achieve targeted delivery of chemotherapeutics into malignant tissues are a critical point for efficient diagnosis and therapy. In this case, bovine serum albumin (BSA) was conjugated with cetuximab–valine–citrulline (vc)–doxorubicin (DOX) to target...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ye, Zixuan, Zhang, Yue, Liu, Yuanfen, Liu, Yanyan, Tu, Jiasheng, Shen, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009551/ https://www.ncbi.nlm.nih.gov/pubmed/33814909 http://dx.doi.org/10.2147/IJN.S289228

Ejemplares similares

Binding of estrogen receptor with estrogen conjugated to bovine serum albumin (BSA)
por: Taguchi, Yasuto, et al.
Publicado: (2004)

Cetuximab-Coated Thermo-Sensitive Liposomes Loaded with Magnetic Nanoparticles and Doxorubicin for Targeted EGFR-Expressing Breast Cancer Combined Therapy
por: Dorjsuren, Buyankhishig, et al.
Publicado: (2020)

Spectroscopic Study on the Interaction between Naphthalimide-Polyamine Conjugates and Bovine Serum Albumin (BSA)
por: Tian, Zhi-Yong, et al.
Publicado: (2015)

STUDIES ON THE INTERACTION BETWEEN TRIPTOLIDE AND BOVINE SERUM ALBUMIN (BSA) BY SPECTROSCOPIC AND MOLECULAR MODELING METHODS
por: Wang, Haidong, et al.
Publicado: (2016)

Glycation does not modify bovine serum albumin (BSA)-induced reduction of rat aortic relaxation: The response to glycated and nonglycated BSA is lost in metabolic syndrome
por: Rubio-Ruiz, Maria Esther, et al.
Publicado: (2008)

Glutamic acid–valine–citrulline linkers ensure stability and efficacy of antibody–drug conjugates in mice
por: Anami, Yasuaki, et al.
Publicado: (2018)

Diverse metabolic response of cancer cells treated with a (213)Bi-anti-EGFR-immunoconjugate
por: Feuerecker, Benedikt, et al.
Publicado: (2021)

Targeted Therapy With Immunoconjugates for Multiple Myeloma
por: Bruins, Wassilis S. C., et al.
Publicado: (2020)

Interaction of Flavonoids from Woodwardia unigemmata with Bovine Serum Albumin (BSA): Application of Spectroscopic Techniques and Molecular Modeling Methods
por: Ma, Rui, et al.
Publicado: (2017)

Self-assembly of bovine serum albumin (BSA)–dextran bio-nanoconjugate: structural, antioxidant and in vitro wound healing studies
por: Rohiwal, Sonali S., et al.
Publicado: (2021)

Effect of Mucilage Extracted from Corchorus olitorius Leaves on Bovine Serum Albumin (BSA)-Stabilized Oil-in-Water Emulsions
por: Kim, Do-Yeong, et al.
Publicado: (2022)

Alpha-Particle Emitting (213)Bi-Anti-EGFR Immunoconjugates Eradicate Tumor Cells Independent of Oxygenation
por: Wulbrand, Christian, et al.
Publicado: (2013)

Enhanced Cellular Uptake and Pharmacokinetic Characteristics of Doxorubicin-Valine Amide Prodrug
por: Park, Yohan, et al.
Publicado: (2016)

Correction: Self-assembly of bovine serum albumin (BSA)–dextran bio-nanoconjugate: structural, antioxidant and in vitro wound healing studies
por: Rohiwal, Sonali S., et al.
Publicado: (2021)

JIG V.C.
por: Roux, J M
Publicado: (1986)

Probing the Binding Sites of Antibiotic Drugs Doxorubicin and N-(trifluoroacetyl) Doxorubicin with Human and Bovine Serum Albumins
por: Agudelo, Daniel, et al.
Publicado: (2012)

Characterizing the Effects of VPA, VC and RCCS on Rabbit Keratocytes onto Decellularized Bovine Cornea
por: Dai, Ying, et al.
Publicado: (2012)

Time‐to‐Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine‐Citrulline‐Monomethylauristatin E Antibody–Drug Conjugates
por: Kågedal, Matts, et al.
Publicado: (2019)

Immunoconjugates for Osteosarcoma Therapy: Preclinical Experiences and Future Perspectives
por: Mercatelli, Daniele, et al.
Publicado: (2018)

Immunization with Bovine Serum Albumin (BSA) in Oil-Adjuvant Elicits IgM Antibody Response in Chinese Soft-Shelled Turtle (Pelodiscus Sinensis)
por: Xu, Cheng, et al.
Publicado: (2020)

Influence of Varying Dietary Protein Levels on Glycation of Albumin, Tryptophan and Valine in the Plasma of Chickens
por: Honma, Ayaka, et al.
Publicado: (2017)

VC in HEP: Status and Perpective
por: Galvez, Philippe
Publicado: (2012)

Neutron-proton total cross-sections between 8 GeVc and 21 GeVc
por: Engler, J, et al.
Publicado: (1970)

Lost in interpretation: should the highest VC value be used to calculate the FEV(1)/VC ratio?
por: Fortis, Spyridon
Publicado: (2016)

Preparation and preclinical evaluation of humanised A33 immunoconjugates for radioimmunotherapy.
por: King, D. J., et al.
Publicado: (1995)

Higher Cytokine and Opsonizing Antibody Production Induced by Bovine Serum Albumin (BSA)-Conjugated Tetrasaccharide Related to Streptococcus pneumoniae Type 3 Capsular Polysaccharide
por: Kurbatova, Ekaterina A., et al.
Publicado: (2020)

Engineered bovine serum albumin-based nanoparticles with pH-sensitivity for doxorubicin delivery and controlled release
por: Yang, Zhihang, et al.
Publicado: (2020)

Optimization of the preparation process of vinblastine sulfate (VBLS)-loaded folateconjugated bovine serum albumin (BSA) nanoparticles for tumor-targeted drug delivery using response surface methodology (RSM)
por: Zu, Yuangang, et al.
Publicado: (2009)

Autoantibodies against citrullinated serum albumin in patients with rheumatoid arthritis
por: Hefton, Amanda, et al.
Publicado: (2019)

A Vc Implementation of TGeoPcon
por: Valles Martin, Juan
Publicado: (2013)

Intratumoral Injection of an Adriamycin Immunoconjugate against Human Pancreatic Cancer Xenografts
por: Kondo, Yasuyuki, et al.
Publicado: (1995)

Cytotoxicity of Selenium Immunoconjugates against Triple Negative Breast Cancer Cells
por: Khandelwal, Soni, et al.
Publicado: (2018)

Cetuximab-Modified Human Serum Albumin Nanoparticles Co-Loaded with Doxorubicin and MDR1 siRNA for the Treatment of Drug-Resistant Breast Tumors
por: Yang, Xin, et al.
Publicado: (2021)

Co-delivery of Cyclopamine and Doxorubicin Mediated by Bovine Serum Albumin Nanoparticles Reverses Doxorubicin Resistance in Breast Cancer by Down-regulating P-glycoprotein Expression
por: Lu, Yong-lin, et al.
Publicado: (2019)

Enhanced cytotoxic activity of cetuximab in EGFR-positive lung cancer by conjugating with gold nanoparticles
por: Qian, Yichun, et al.
Publicado: (2014)

A Novel Active Targeting Preparation, Vinorelbine Tartrate (VLBT) Encapsulated by Folate-Conjugated Bovine Serum Albumin (BSA) Nanoparticles: Preparation, Characterization and in Vitro Release Study
por: Li, Yong, et al.
Publicado: (2012)

An EGFR‐targeting antibody–drug conjugate LR004‐VC‐MMAE: potential in esophageal squamous cell carcinoma and other malignancies
por: Hu, Xin‐yue, et al.
Publicado: (2018)

JIG V.C. - Dessin P.00041
por: Roux, J M
Publicado: (1986)

Preparation of folic acid-conjugated, doxorubicin-loaded, magnetic bovine serum albumin nanospheres and their antitumor effects in vitro and in vivo
por: Yang, Rui, et al.
Publicado: (2014)

Radiolabeled Cetuximab Conjugates for EGFR Targeted Cancer Diagnostics and Therapy (†)
por: Sihver, Wiebke, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_pqa5ktv6ju0e26ai0gq1mqj8ea