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Dynamic Na(+)/H(+) exchanger 1 (NHE1) – calmodulin complexes of varying stoichiometry and structure regulate Ca(2+)-dependent NHE1 activation
Calmodulin (CaM) engages in Ca(2+)-dependent interactions with numerous proteins, including a still incompletely understood physical and functional interaction with the human Na(+)/H(+)-exchanger NHE1. Using nuclear magnetic resonance (NMR) spectroscopy, isothermal titration calorimetry, and fibrobl...
Autores principales: | Sjøgaard-Frich, Lise M, Prestel, Andreas, Pedersen, Emilie S, Severin, Marc, Kristensen, Kristian Kølby, Olsen, Johan G, Kragelund, Birthe B, Pedersen, Stine Falsig |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009664/ https://www.ncbi.nlm.nih.gov/pubmed/33655882 http://dx.doi.org/10.7554/eLife.60889 |
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