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Time Course of Alterations in Adult Spinal Motoneuron Properties in the SOD1(G93A) Mouse Model of ALS

Although amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease, motoneuron electrical properties are already altered during embryonic development. Motoneurons must therefore exhibit a remarkable capacity for homeostatic regulation to maintain a normal motor output for most...

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Detalles Bibliográficos
Autores principales: Huh, Seoan, Heckman, Charles J., Manuel, Marin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009670/
https://www.ncbi.nlm.nih.gov/pubmed/33632815
http://dx.doi.org/10.1523/ENEURO.0378-20.2021