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Automatic Detection of Obstructive Sleep Apnea Events Using a Deep CNN-LSTM Model

Obstructive sleep apnea (OSA) is a common sleep-related respiratory disorder. Around the world, more and more people are suffering from OSA. Because of the limitation of monitor equipment, many people with OSA remain undetected. Therefore, we propose a sleep-monitoring model based on single-channel...

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Autores principales: Zhang, Junming, Tang, Zhen, Gao, Jinfeng, Lin, Li, Liu, Zhiliang, Wu, Haitao, Liu, Fang, Yao, Ruxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009718/
https://www.ncbi.nlm.nih.gov/pubmed/33859679
http://dx.doi.org/10.1155/2021/5594733
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author Zhang, Junming
Tang, Zhen
Gao, Jinfeng
Lin, Li
Liu, Zhiliang
Wu, Haitao
Liu, Fang
Yao, Ruxian
author_facet Zhang, Junming
Tang, Zhen
Gao, Jinfeng
Lin, Li
Liu, Zhiliang
Wu, Haitao
Liu, Fang
Yao, Ruxian
author_sort Zhang, Junming
collection PubMed
description Obstructive sleep apnea (OSA) is a common sleep-related respiratory disorder. Around the world, more and more people are suffering from OSA. Because of the limitation of monitor equipment, many people with OSA remain undetected. Therefore, we propose a sleep-monitoring model based on single-channel electrocardiogram using a convolutional neural network (CNN), which can be used in portable OSA monitor devices. To learn different scale features, the first convolution layer comprises three types of filters. The long short-term memory (LSTM) is used to learn the long-term dependencies such as the OSA transition rules. The softmax function is connected to the final fully connected layer to obtain the final decision. To detect a complete OSA event, the raw ECG signals are segmented by a 10 s overlapping sliding window. The proposed model is trained with the segmented raw signals and is subsequently tested to evaluate its event detection performance. According to experiment analysis, the proposed model exhibits Cohen's kappa coefficient of 0.92, a sensitivity of 96.1%, a specificity of 96.2%, and an accuracy of 96.1% with respect to the Apnea-ECG dataset. The proposed model is significantly higher than the results from the baseline method. The results prove that our approach could be a useful tool for detecting OSA on the basis of a single-lead ECG.
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spelling pubmed-80097182021-04-14 Automatic Detection of Obstructive Sleep Apnea Events Using a Deep CNN-LSTM Model Zhang, Junming Tang, Zhen Gao, Jinfeng Lin, Li Liu, Zhiliang Wu, Haitao Liu, Fang Yao, Ruxian Comput Intell Neurosci Research Article Obstructive sleep apnea (OSA) is a common sleep-related respiratory disorder. Around the world, more and more people are suffering from OSA. Because of the limitation of monitor equipment, many people with OSA remain undetected. Therefore, we propose a sleep-monitoring model based on single-channel electrocardiogram using a convolutional neural network (CNN), which can be used in portable OSA monitor devices. To learn different scale features, the first convolution layer comprises three types of filters. The long short-term memory (LSTM) is used to learn the long-term dependencies such as the OSA transition rules. The softmax function is connected to the final fully connected layer to obtain the final decision. To detect a complete OSA event, the raw ECG signals are segmented by a 10 s overlapping sliding window. The proposed model is trained with the segmented raw signals and is subsequently tested to evaluate its event detection performance. According to experiment analysis, the proposed model exhibits Cohen's kappa coefficient of 0.92, a sensitivity of 96.1%, a specificity of 96.2%, and an accuracy of 96.1% with respect to the Apnea-ECG dataset. The proposed model is significantly higher than the results from the baseline method. The results prove that our approach could be a useful tool for detecting OSA on the basis of a single-lead ECG. Hindawi 2021-03-22 /pmc/articles/PMC8009718/ /pubmed/33859679 http://dx.doi.org/10.1155/2021/5594733 Text en Copyright © 2021 Junming Zhang et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhang, Junming
Tang, Zhen
Gao, Jinfeng
Lin, Li
Liu, Zhiliang
Wu, Haitao
Liu, Fang
Yao, Ruxian
Automatic Detection of Obstructive Sleep Apnea Events Using a Deep CNN-LSTM Model
title Automatic Detection of Obstructive Sleep Apnea Events Using a Deep CNN-LSTM Model
title_full Automatic Detection of Obstructive Sleep Apnea Events Using a Deep CNN-LSTM Model
title_fullStr Automatic Detection of Obstructive Sleep Apnea Events Using a Deep CNN-LSTM Model
title_full_unstemmed Automatic Detection of Obstructive Sleep Apnea Events Using a Deep CNN-LSTM Model
title_short Automatic Detection of Obstructive Sleep Apnea Events Using a Deep CNN-LSTM Model
title_sort automatic detection of obstructive sleep apnea events using a deep cnn-lstm model
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009718/
https://www.ncbi.nlm.nih.gov/pubmed/33859679
http://dx.doi.org/10.1155/2021/5594733
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