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Replicating bacterium-vectored vaccine expressing SARS-CoV-2 Membrane and Nucleocapsid proteins protects against severe COVID-19-like disease in hamsters

To generate an inexpensive readily manufactured COVID-19 vaccine, we employed the LVS ΔcapB vector platform, previously used to generate potent candidate vaccines against Select Agent diseases tularemia, anthrax, plague, and melioidosis. Vaccines expressing SARS-CoV-2 structural proteins are constru...

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Detalles Bibliográficos
Autores principales:	Jia, Qingmei, Bielefeldt-Ohmann, Helle, Maison, Rachel M., Masleša-Galić, Saša, Cooper, Sarah K., Bowen, Richard A., Horwitz, Marcus A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009914/ https://www.ncbi.nlm.nih.gov/pubmed/33785745 http://dx.doi.org/10.1038/s41541-021-00321-8

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