Astrocytic atrophy as a pathological feature of Parkinson’s disease with LRRK2 mutation

The principal hallmark of Parkinson’s disease (PD) is the selective neurodegeneration of dopaminergic neurones. Mounting evidence suggests that astrocytes may contribute to dopaminergic neurodegeneration through decreased homoeostatic support and deficient neuroprotection. In this study, we generate...

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Detalles Bibliográficos
Autores principales: Ramos-Gonzalez, Paula, Mato, Susana, Chara, Juan Carlos, Verkhratsky, Alexei, Matute, Carlos, Cavaliere, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8009947/
https://www.ncbi.nlm.nih.gov/pubmed/33785762
http://dx.doi.org/10.1038/s41531-021-00175-w

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