Methamphetamine and HIV-Tat Protein Synergistically Induce Oxidative Stress and Blood-Brain Barrier Damage via Transient Receptor Potential Melastatin 2 Channel

Synergistic impairment of the blood-brain barrier (BBB) induced by methamphetamine (METH) and HIV-Tat protein increases the risk of HIV-associated neurocognitive disorders (HAND) in HIV-positive METH abusers. Studies have shown that oxidative stress plays a vital role in METH- and HIV-Tat-induced da...

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Detalles Bibliográficos
Autores principales: Huang, Jian, Zhang, Ruilin, Wang, Shangwen, Zhang, Dongxian, Leung, Chi-Kwan, Yang, Genmeng, Li, Yuanyuan, Liu, Liu, Xu, Yue, Lin, Shucheng, Wang, Chan, Zeng, Xiaofeng, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010131/
https://www.ncbi.nlm.nih.gov/pubmed/33815104
http://dx.doi.org/10.3389/fphar.2021.619436

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