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A Therapeutic Strategy to Combat HIV-1 Latently Infected Cells With a Combination of Latency-Reversing Agents Containing DAG-Lactone PKC Activators
Advances in antiviral therapy have dramatically improved the therapeutic effects on HIV type 1 (HIV-1) infection. However, even with potent combined antiretroviral therapy, HIV-1 latently infected cells cannot be fully eradicated. Latency-reversing agents (LRAs) are considered a potential tool for e...
Autores principales: | Matsuda, Kouki, Kobayakawa, Takuya, Kariya, Ryusho, Tsuchiya, Kiyoto, Ryu, Shoraku, Tsuji, Kohei, Ishii, Takahiro, Gatanaga, Hiroyuki, Yoshimura, Kazuhisa, Okada, Seiji, Hamada, Akinobu, Mitsuya, Hiroaki, Tamamura, Hirokazu, Maeda, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010149/ https://www.ncbi.nlm.nih.gov/pubmed/33815322 http://dx.doi.org/10.3389/fmicb.2021.636276 |
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