Monocytes From Patients With Macrophage Activation Syndrome and Secondary Hemophagocytic Lymphohistiocytosis Are Hyperresponsive to Interferon Gamma

OBJECTIVE: To investigate the activation of the IFNγ signaling pathway in monocytes of patients with secondary hemophagocytic lymphohistiocytosis (sHLH)/macrophage activation syndrome (MAS) and to evaluate whether levels of phosphorylated STAT1 represent a biomarker for the identification of patient...

Descripción completa

Detalles Bibliográficos
Autores principales: Pascarella, Antonia, Bracaglia, Claudia, Caiello, Ivan, Arduini, Alessia, Moneta, Gian Marco, Rossi, Marianna Nicoletta, Matteo, Valentina, Pardeo, Manuela, De Benedetti, Fabrizio, Prencipe, Giusi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010171/
https://www.ncbi.nlm.nih.gov/pubmed/33815425
http://dx.doi.org/10.3389/fimmu.2021.663329

Ejemplares similares

Ejemplares similares