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β-Hexosaminidases Along the Secretory Pathway of Nicotiana benthamiana Have Distinct Specificities Toward Engineered Helminth N-Glycans on Recombinant Glycoproteins
Secretions of parasitic worms (helminths) contain a wide collection of immunomodulatory glycoproteins with the potential to treat inflammatory disorders, like autoimmune diseases. Yet, the identification of single molecules that can be developed into novel biopharmaceuticals is hampered by the limit...
Autores principales: | Alvisi, Nicolò, van Noort, Kim, Dwiani, Sarlita, Geschiere, Nathan, Sukarta, Octavina, Varossieau, Koen, Nguyen, Dieu-Linh, Strasser, Richard, Hokke, Cornelis H., Schots, Arjen, Wilbers, Ruud H. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010188/ https://www.ncbi.nlm.nih.gov/pubmed/33815445 http://dx.doi.org/10.3389/fpls.2021.638454 |
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