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A new mathematical model of COVID-19 using real data from Pakistan
We propose a new mathematical model to investigate the recent outbreak of the coronavirus disease (COVID-19). The model is studied qualitatively using stability theory of differential equations and the basic reproductive number that represents an epidemic indicator is obtained from the largest eigen...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010333/ https://www.ncbi.nlm.nih.gov/pubmed/33816093 http://dx.doi.org/10.1016/j.rinp.2021.104098 |
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author | Peter, Olumuyiwa James Qureshi, Sania Yusuf, Abdullahi Al-Shomrani, Mohammed Idowu, Abioye Abioye |
author_facet | Peter, Olumuyiwa James Qureshi, Sania Yusuf, Abdullahi Al-Shomrani, Mohammed Idowu, Abioye Abioye |
author_sort | Peter, Olumuyiwa James |
collection | PubMed |
description | We propose a new mathematical model to investigate the recent outbreak of the coronavirus disease (COVID-19). The model is studied qualitatively using stability theory of differential equations and the basic reproductive number that represents an epidemic indicator is obtained from the largest eigenvalue of the next-generation matrix. The global asymptotic stability conditions for the disease free equilibrium are obtained. The real COVID-19 incidence data entries from 01 July, 2020 to 14 August, 2020 in the country of Pakistan are used for parameter estimation thereby getting fitted values for the biological parameters. Sensitivity analysis is performed in order to determine the most sensitive parameters in the proposed model. To view more features of the state variables in the proposed model, we perform numerical simulations by using different values of some essential parameters. Moreover, profiles of the reproduction number through contour plots have been biologically explained. |
format | Online Article Text |
id | pubmed-8010333 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Authors. Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-80103332021-03-31 A new mathematical model of COVID-19 using real data from Pakistan Peter, Olumuyiwa James Qureshi, Sania Yusuf, Abdullahi Al-Shomrani, Mohammed Idowu, Abioye Abioye Results Phys Article We propose a new mathematical model to investigate the recent outbreak of the coronavirus disease (COVID-19). The model is studied qualitatively using stability theory of differential equations and the basic reproductive number that represents an epidemic indicator is obtained from the largest eigenvalue of the next-generation matrix. The global asymptotic stability conditions for the disease free equilibrium are obtained. The real COVID-19 incidence data entries from 01 July, 2020 to 14 August, 2020 in the country of Pakistan are used for parameter estimation thereby getting fitted values for the biological parameters. Sensitivity analysis is performed in order to determine the most sensitive parameters in the proposed model. To view more features of the state variables in the proposed model, we perform numerical simulations by using different values of some essential parameters. Moreover, profiles of the reproduction number through contour plots have been biologically explained. The Authors. Published by Elsevier B.V. 2021-05 2021-03-31 /pmc/articles/PMC8010333/ /pubmed/33816093 http://dx.doi.org/10.1016/j.rinp.2021.104098 Text en © 2021 The Authors. Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Peter, Olumuyiwa James Qureshi, Sania Yusuf, Abdullahi Al-Shomrani, Mohammed Idowu, Abioye Abioye A new mathematical model of COVID-19 using real data from Pakistan |
title | A new mathematical model of COVID-19 using real data from Pakistan |
title_full | A new mathematical model of COVID-19 using real data from Pakistan |
title_fullStr | A new mathematical model of COVID-19 using real data from Pakistan |
title_full_unstemmed | A new mathematical model of COVID-19 using real data from Pakistan |
title_short | A new mathematical model of COVID-19 using real data from Pakistan |
title_sort | new mathematical model of covid-19 using real data from pakistan |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010333/ https://www.ncbi.nlm.nih.gov/pubmed/33816093 http://dx.doi.org/10.1016/j.rinp.2021.104098 |
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