Cargando…

Isorhamnetin Ameliorates Aspergillus fumigatus Keratitis by Reducing Fungal Load, Inhibiting Pattern-Recognition Receptors and Inflammatory Cytokines

PURPOSE: Isorhamnetin is a natural flavonoid with both antimicrobial and anti-inflammatory properties, but its effect on fungal keratitis (FK) remains unknown. The current study aims to investigate the antifungal and anti-inflammatory effects of isorhamnetin against mouse Aspergillus fumigatus kerat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tian, Xue, Peng, Xudong, Lin, Jing, Zhang, Yingxue, Zhan, Lu, Yin, Jiao, Zhang, Ranran, Zhao, Guiqiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2021
Materias:	Cornea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010362/ https://www.ncbi.nlm.nih.gov/pubmed/33783487 http://dx.doi.org/10.1167/iovs.62.3.38

Ejemplares similares

Gallic Acid Ameliorates Aspergillus Fumigatus Keratitis Through Reducing Fungal Load and Suppressing the Inflammatory Response
por: Luan, Songying, et al.
Publicado: (2022)

The Role of SREC-Ⅰ in Innate Immunity to Aspergillus fumigatus Keratitis
por: Zhang, Ranran, et al.
Publicado: (2021)

Baicalein Protects Against Aspergillus fumigatus Keratitis by Reducing Fungal Load and Inhibiting TSLP-Induced Inflammatory Response
por: Zhu, Yunan, et al.
Publicado: (2021)

The Role of Autophagy in the Innate Immune Response to Fungal Keratitis Caused by Aspergillus fumigatus Infection
por: Li, Chenyu, et al.
Publicado: (2020)

Perillaldehyde Ameliorates Aspergillus fumigatus Keratitis by Activating the Nrf2/HO-1 Signaling Pathway and Inhibiting Dectin-1-Mediated Inflammation
por: Fan, Yiqun, et al.
Publicado: (2020)

Indoleamine 2,3-Dioxygenase Regulates Macrophage Recruitment, Polarization and Phagocytosis in Aspergillus Fumigatus Keratitis
por: Jiang, Nan, et al.
Publicado: (2020)

Honokiol Reduces Fungal Load, Toll-Like Receptor-2, and Inflammatory Cytokines in Aspergillus fumigatus Keratitis
por: Zhan, Lu, et al.
Publicado: (2020)

IL-36α Exerts Proinflammatory Effects in Aspergillus fumigatus Keratitis of Mice Through the Pathway of IL-36α/IL-36R/NF-κB
por: Niu, Yawen, et al.
Publicado: (2021)

TSLP Produced by Aspergillus fumigatus-Stimulated DCs Promotes a Th17 Response Through the JAK/STAT Signaling Pathway in Fungal Keratitis
por: Han, Fang, et al.
Publicado: (2020)

CLEC-1 Acts as a Negative Regulator of Dectin-1 Induced Host Inflammatory Response Signature in Aspergillus fumigatus Keratitis
por: Zhu, Guoqiang, et al.
Publicado: (2021)

0.01% Hypochlorous Acid Treats Aspergillus fumigatus Keratitis in Rats by Reducing Fungal Load and Inhibiting the Inflammatory Response
por: Zhao, Kai, et al.
Publicado: (2023)

ISG15 in Host Defense Against Candida albicans Infection in a Mouse Model of Fungal Keratitis
por: Dong, Chen, et al.
Publicado: (2017)

Prophylactic Knockdown of the miR-183/96/182 Cluster Ameliorates Pseudomonas aeruginosa–Induced Keratitis
por: McClellan, Sharon, et al.
Publicado: (2021)

Benzyl isothiocyanate improves the prognosis of Aspergillus fumigatus keratitis by reducing fungal load and inhibiting Mincle signal pathway
por: Yi, Wendan, et al.
Publicado: (2023)

Norepinephrine as the Intrinsic Contributor to Contact Lens–Induced Pseudomonas aeruginosa Keratitis
por: Zhang, Bi Ning, et al.
Publicado: (2023)

Designed Host Defense Peptides for the Treatment of Bacterial Keratitis
por: Clemens, L. Edward, et al.
Publicado: (2017)

Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis
por: Zhao, Wenyi, et al.
Publicado: (2018)

A Central Role for Sympathetic Nerves in Herpes Stromal Keratitis in Mice
por: Yun, Hongmin, et al.
Publicado: (2016)

Antimicrobial Blue Light Therapy for Infectious Keratitis: Ex Vivo and In Vivo Studies
por: Zhu, Hong, et al.
Publicado: (2017)

Impact of implementation of polymerase chain reaction on diagnosis, treatment, and clinical course of Acanthamoeba keratitis
por: Roth, Mathias, et al.
Publicado: (2023)

Analysis of MicroRNA Expression in Tears of Patients with Herpes Epithelial Keratitis: A Preliminary Study
por: Kim, Yu Jeong, et al.
Publicado: (2022)

Bilateral Limbal Stem Cell Alterations in Patients With Unilateral Herpes Simplex Keratitis and Herpes Zoster Ophthalmicus as Shown by In Vivo Confocal Microscopy
por: Liu, Xintian, et al.
Publicado: (2021)

Innate and Adaptive Gene Single Nucleotide Polymorphisms Associated With Susceptibility of Severe Inflammatory Complications in Acanthamoeba Keratitis
por: Carnt, Nicole A., et al.
Publicado: (2021)

Antimicrobial Studies Using the Therapeutic Tissue Cross-Linking Agent, Sodium Hydroxymethylglycinate: Implication for Treating Infectious Keratitis
por: Rapuano, Patrick B., et al.
Publicado: (2018)

Inhibition of miR-665-3p Enhances Autophagy and Alleviates Inflammation in Fusarium solani-Induced Keratitis
por: Guo, Qunqin, et al.
Publicado: (2021)

Role of IL-36γ/IL-36R Signaling in Corneal Innate Defense Against Candida albicans Keratitis
por: Dai, Chenyang, et al.
Publicado: (2021)

METTL3 Attenuates Inflammation in Fusarium solani–Induced Keratitis via the PI3K/AKT Signaling Pathway
por: Huang, Liwei, et al.
Publicado: (2022)

MiR-223-3p Regulates Autophagy and Inflammation by Targeting ATG16L1 in Fusarium solani–Induced Keratitis
por: Tang, Hanfeng, et al.
Publicado: (2022)

Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis
por: Mehta, Hijab, et al.
Publicado: (2008)

Inhibition of the m6A Methyltransferase METTL3 Attenuates the Inflammatory Response in Fusarium solani-Induced Keratitis via the NF-κB Signaling Pathway
por: Tang, Hanfeng, et al.
Publicado: (2022)

Hyperkeratinization and Proinflammatory Cytokine Expression in Meibomian Glands Induced by Staphylococcus aureus
por: Chen, Hua, et al.
Publicado: (2021)

Comparison of Corneal Collagen Cross-Linking and Voriconazole Treatments in Experimental Fungal Keratitis for Aspergillus fumigatus
por: Zhao, Zhennan, et al.
Publicado: (2022)

Lipoxin A4 alleviates inflammation in Aspergillus fumigatus–stimulated human corneal epithelial cells by Nrf2/HO-1 signaling pathway
por: Peng, Xudong, et al.
Publicado: (2022)

The Differential Expression of Cytokines and Growth Factors After SMILE Compared With FS-LASIK in Rabbits
por: Liu, Lingjia, et al.
Publicado: (2020)

Chlorhexidine gluconate 0.2% as a treatment for recalcitrant fungal keratitis in Uganda: a pilot study
por: Arunga, Simon, et al.
Publicado: (2021)

Integrated Stress Response Regulation of Corneal Epithelial Cell Motility and Cytokine Production
por: Chu, Hsiao-Sang, et al.
Publicado: (2022)

Comparison of Accelerated and Standard Corneal Collagen Cross-Linking Treatments in Experimental Fungal Keratitis for Aspergillus fumigatus
por: Wei, Anji, et al.
Publicado: (2022)

Adipose Mesenchymal Stem Cell-Derived Exosomes Promote the Regeneration of Corneal Endothelium Through Ameliorating Senescence
por: Ryu, Yunkyoung, et al.
Publicado: (2023)

Aspergillus fumigatus keratitis following intracorneal ring segment implantation
por: Shihadeh, Wisam A
Publicado: (2012)

Aim2 Deficiency Ameliorates Lacrimal Gland Destruction and Corneal Epithelium Defects in an Experimental Dry Eye Model
por: Chen, Yu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ovq2u7rg0n4jnflret39g96vbn