Discovery of a novel lactate dehydrogenase tetramerization domain using epitope mapping and peptides

Despite being initially regarded as a metabolic waste product, lactate is now considered to serve as a primary fuel for the tricarboxylic acid cycle in cancer cells. At the core of lactate metabolism, lactate dehydrogenases (LDHs) catalyze the interconversion of lactate to pyruvate and as such repre...

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Detalles Bibliográficos
Autores principales: Thabault, Léopold, Liberelle, Maxime, Koruza, Katarina, Yildiz, Esra, Joudiou, Nicolas, Messens, Joris, Brisson, Lucie, Wouters, Johan, Sonveaux, Pierre, Frédérick, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010463/
https://www.ncbi.nlm.nih.gov/pubmed/33607109
http://dx.doi.org/10.1016/j.jbc.2021.100422

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