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Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers

Voltage-gated sodium (Na(V)) channels, initially characterized in excitable cells, have been shown to be aberrantly expressed in non-excitable cancer tissues and cells from epithelial origins such as in breast, lung, prostate, colon, and cervix, whereas they are not expressed in cognate non-cancer t...

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Detalles Bibliográficos
Autores principales: Lopez-Charcas, Osbaldo, Pukkanasut, Piyasuda, Velu, Sadanandan E., Brackenbury, William J., Hales, Tim G., Besson, Pierre, Gomora, Juan Carlos, Roger, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010468/
https://www.ncbi.nlm.nih.gov/pubmed/33817575
http://dx.doi.org/10.1016/j.isci.2021.102270