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Evidence for a role of phenotypic mutations in virus adaptation
Viruses interact extensively with the host molecular machinery, but the underlying mechanisms are poorly understood. Bacteriophage T7 recruits the small protein thioredoxin of the Escherichia coli host as an essential processivity factor for the viral DNA polymerase. We challenged the phage to propa...
Autores principales: | Luzon-Hidalgo, Raquel, Risso, Valeria A., Delgado, Asuncion, Andrés-León, Eduardo, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010470/ https://www.ncbi.nlm.nih.gov/pubmed/33817569 http://dx.doi.org/10.1016/j.isci.2021.102257 |
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