The role of striated muscle Pik3r1 in glucose and protein metabolism following chronic glucocorticoid exposure

Chronic glucocorticoid exposure causes insulin resistance and muscle atrophy in skeletal muscle. We previously identified phosphoinositide-3-kinase regulatory subunit 1 (Pik3r1) as a primary target gene of skeletal muscle glucocorticoid receptors involved in the glucocorticoid-mediated suppression o...

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Detalles Bibliográficos
Autores principales: Chen, Tzu-Chieh, Kuo, Taiyi, Dandan, Mohamad, Lee, Rebecca A., Chang, Maggie, Villivalam, Sneha D., Liao, Szu-Chi, Costello, Damian, Shankaran, Mahalakshmi, Mohammed, Hussein, Kang, Sona, Hellerstein, Marc K., Wang, Jen-Chywan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010618/
https://www.ncbi.nlm.nih.gov/pubmed/33567340
http://dx.doi.org/10.1016/j.jbc.2021.100395

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