Cargando…
Conjugated secondary 12α-hydroxylated bile acids promote liver fibrogenesis
BACKGROUND: Significantly elevated serum and hepatic bile acid (BA) concentrations have been known to occur in patients with liver fibrosis. However, the roles of different BA species in liver fibrogenesis are not fully understood. METHODS: We quantitatively measured blood BA concentrations in nonal...
Autores principales: | Xie, Guoxiang, Jiang, Runqiu, Wang, Xiaoning, Liu, Ping, Zhao, Aihua, Wu, Yiran, Huang, Fengjie, Liu, Zhipeng, Rajani, Cynthia, Zheng, Xiaojiao, Qiu, Jiannan, Zhang, Xiaoling, Zhao, Suwen, Bian, Hua, Gao, Xin, Sun, Beicheng, Jia, Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010625/ https://www.ncbi.nlm.nih.gov/pubmed/33752128 http://dx.doi.org/10.1016/j.ebiom.2021.103290 |
Ejemplares similares
-
Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure
por: Xie, Guoxiang, et al.
Publicado: (2018) -
Increased levels of conjugated bile acids are associated with human bile reflux gastritis
por: Zhao, Aihua, et al.
Publicado: (2020) -
A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility
por: Wei, Meilin, et al.
Publicado: (2020) -
Bile acid is a significant host factor shaping the gut microbiome of diet-induced obese mice
por: Zheng, Xiaojiao, et al.
Publicado: (2017) -
Sex-dependent effects on gut microbiota regulate hepatic carcinogenic outcomes
por: Xie, Guoxiang, et al.
Publicado: (2017)