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α-Synuclein Up-regulates Monoamine Oxidase A Expression and Activity via Trans-Acting Transcription Factor 1

Abnormal α-Synuclein (α-SYN) aggregates are the pathological hallmarks of Parkinson’s disease (PD), which may affect dopamine (DA) neuron function and DA metabolism. Monoamine oxidase A (MAOA) is an enzyme located on the outer mitochondrial membrane that catalyzes the oxidative deamination of DA. Bo...

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Detalles Bibliográficos
Autores principales:	Jia, Congcong, Cheng, Cheng, Li, Tianbai, Chen, Xi, Yang, Yuting, Liu, Xinyao, Li, Song, Le, Weidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010665/ https://www.ncbi.nlm.nih.gov/pubmed/33815093 http://dx.doi.org/10.3389/fnagi.2021.653379

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