An elevated polyclonal free light chain level reflects a strong interferon signature in patients with systemic autoimmune diseases

High amount of polyclonal free light chains (FLC) are reported in systemic autoimmune diseases (SAD) and we took advantage of the PRECISESADS study to better characterize them. Serum FLC levels were explored in 1979 patients with SAD (RA, SLE, SjS, Scl, APS, UCTD, MCTD) and 614 healthy controls. Inf...

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Detalles Bibliográficos
Autores principales: Bettacchioli, Eléonore, Le Gaffric, Christelle, Mazeas, Margaux, Borghi, Maria Orietta, Frostegard, Johan, Barturen, Guillermo, Makowska, Zuzanna, Babei, Sepideh, Lesche, Ralf, Meroni, Pier Luigi, Alarcon-Riquelme, Marta E., Renaudineau, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010703/
https://www.ncbi.nlm.nih.gov/pubmed/33817614
http://dx.doi.org/10.1016/j.jtauto.2021.100090

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