Molecular basis of tail-anchored integral membrane protein recognition by the cochaperone Sgt2

The targeting and insertion of tail-anchored (TA) integral membrane proteins (IMPs) into the correct membrane is critical for cellular homeostasis. The fungal protein Sgt2, and its human homolog SGTA, is the entry point for clients to the guided entry of tail-anchored protein (GET) pathway, which ta...

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Detalles Bibliográficos
Autores principales: Lin, Ku-Feng, Fry, Michelle Y., Saladi, Shyam M., Clemons, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010706/
https://www.ncbi.nlm.nih.gov/pubmed/33610544
http://dx.doi.org/10.1016/j.jbc.2021.100441

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