The thermogenic characteristics of adipocytes are dependent on the regulation of iron homeostasis

The development of thermogenic adipocytes concurs with mitochondrial biogenesis, an iron-dependent pathway. Iron regulatory proteins (IRP) 1 and 2 are RNA-binding proteins that regulate intracellular iron homeostasis. IRPs bind to the iron-response element (IRE) of their target mRNAs, balancing iron...

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Detalles Bibliográficos
Autores principales: Yook, Jin-Seon, You, Mikyoung, Kim, Yongeun, Zhou, Mi, Liu, Zhenhua, Kim, Young-Cheul, Lee, Jaekwon, Chung, Soonkyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010711/
https://www.ncbi.nlm.nih.gov/pubmed/33631196
http://dx.doi.org/10.1016/j.jbc.2021.100452

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