Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2

Repurposing drugs as treatments for COVID-19 has drawn much attention. A common strategy has been to screen for established drugs, typically developed for other indications, that are antiviral in cells or organisms. Intriguingly, most of the drugs that have emerged from these campaigns, though diver...

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Detalles Bibliográficos
Autores principales: Tummino, Tia A., Rezelj, Veronica V., Fischer, Benoit, Fischer, Audrey, O’Meara, Matthew J., Monel, Blandine, Vallet, Thomas, Zhang, Ziyang, Alon, Assaf, O’Donnell, Henry R., Lyu, Jiankun, Schadt, Heiko, White, Kris M, Krogan, Nevan J., Urban, Laszlo, Shokat, Kevan M., Kruse, Andrew C., García-Sastre, Adolfo, Schwartz, Olivier, Moretti, Francesca, Vignuzzi, Marco, Pognan, Francois, Shoichet, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010720/
https://www.ncbi.nlm.nih.gov/pubmed/33791693
http://dx.doi.org/10.1101/2021.03.23.436648

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