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BTK inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): A Systematic Review
IMPORTANCE: The Bruton tyrosine kinase (BTK) regulates B cell and macrophage signaling, development, survival, and activation. BTK inhibition was shown to protect against lethal influenza-induced acute lung injury in mice. Inhibiting BTK has been hypothesized to ameliorate lung injury in patients wi...
Autores principales: | Stack, Michael, Sacco, Keith, Castagnoli, Riccardo, Livinski, Alicia A., Notarangelo, Luigi D., Lionakis, Michail S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010740/ https://www.ncbi.nlm.nih.gov/pubmed/33791689 http://dx.doi.org/10.21203/rs.3.rs-319342/v1 |
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