BTK inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): A Systematic Review

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IMPORTANCE: The Bruton tyrosine kinase (BTK) regulates B cell and macrophage signaling, development, survival, and activation. BTK inhibition was shown to protect against lethal influenza-induced acute lung injury in mice. Inhibiting BTK has been hypothesized to ameliorate lung injury in patients wi...

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Detalles Bibliográficos
Autores principales: Stack, Michael, Sacco, Keith, Castagnoli, Riccardo, Livinski, Alicia A., Notarangelo, Luigi D., Lionakis, Michail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010740/
https://www.ncbi.nlm.nih.gov/pubmed/33791689
http://dx.doi.org/10.21203/rs.3.rs-319342/v1
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