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From loss to recovery: how to effectively assess chemosensory impairments during COVID-19 pandemic

Chemosensory impairments have been established as a specific indicator of COVID-19. They affect most patients and may persist long past the resolution of respiratory symptoms, representing an unprecedented medical challenge. Since the SARS-CoV-2 pandemic started, we now know much more about smell, t...

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Autores principales: Cecchetto, Cinzia, Di Pizio, Antonella, Genovese, Federica, Calcinoni, Orietta, Macchi, Alberto, Dunkel, Andreas, Ohla, Kathrin, Spinelli, Sara, Farruggia, Michael C., Joseph, Paule V., Menini, Anna, Cantone, Elena, Dinnella, Caterina, Cecchini, Maria Paola, D’Errico, Anna, Mucignat-Caretta, Carla, Parma, Valentina, Dibattista, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010774/
https://www.ncbi.nlm.nih.gov/pubmed/33791742
http://dx.doi.org/10.1101/2021.03.25.21254253
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author Cecchetto, Cinzia
Di Pizio, Antonella
Genovese, Federica
Calcinoni, Orietta
Macchi, Alberto
Dunkel, Andreas
Ohla, Kathrin
Spinelli, Sara
Farruggia, Michael C.
Joseph, Paule V.
Menini, Anna
Cantone, Elena
Dinnella, Caterina
Cecchini, Maria Paola
D’Errico, Anna
Mucignat-Caretta, Carla
Parma, Valentina
Dibattista, Michele
author_facet Cecchetto, Cinzia
Di Pizio, Antonella
Genovese, Federica
Calcinoni, Orietta
Macchi, Alberto
Dunkel, Andreas
Ohla, Kathrin
Spinelli, Sara
Farruggia, Michael C.
Joseph, Paule V.
Menini, Anna
Cantone, Elena
Dinnella, Caterina
Cecchini, Maria Paola
D’Errico, Anna
Mucignat-Caretta, Carla
Parma, Valentina
Dibattista, Michele
author_sort Cecchetto, Cinzia
collection PubMed
description Chemosensory impairments have been established as a specific indicator of COVID-19. They affect most patients and may persist long past the resolution of respiratory symptoms, representing an unprecedented medical challenge. Since the SARS-CoV-2 pandemic started, we now know much more about smell, taste, and chemesthesis loss associated with COVID-19. However, the temporal dynamics and characteristics of recovery are still unknown. Here, capitalizing on data from the Global Consortium for Chemosensory Research (GCCR) crowdsourced survey, we assessed chemosensory abilities after the resolution of respiratory symptoms in participants diagnosed with COVID-19 during the first wave of the pandemic in Italy. This analysis led to the identification of two patterns of chemosensory recovery, limited (partial) and substantial, which were found to be associated with differential age, degrees of chemosensory loss, and regional patterns. Uncovering the self-reported phenomenology of recovery from smell, taste, and chemesthetic disorders is the first, yet essential step, to provide healthcare professionals with the tools to take purposeful and targeted action to address chemosensory disorders and its severe discomfort.
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spelling pubmed-80107742021-04-01 From loss to recovery: how to effectively assess chemosensory impairments during COVID-19 pandemic Cecchetto, Cinzia Di Pizio, Antonella Genovese, Federica Calcinoni, Orietta Macchi, Alberto Dunkel, Andreas Ohla, Kathrin Spinelli, Sara Farruggia, Michael C. Joseph, Paule V. Menini, Anna Cantone, Elena Dinnella, Caterina Cecchini, Maria Paola D’Errico, Anna Mucignat-Caretta, Carla Parma, Valentina Dibattista, Michele medRxiv Article Chemosensory impairments have been established as a specific indicator of COVID-19. They affect most patients and may persist long past the resolution of respiratory symptoms, representing an unprecedented medical challenge. Since the SARS-CoV-2 pandemic started, we now know much more about smell, taste, and chemesthesis loss associated with COVID-19. However, the temporal dynamics and characteristics of recovery are still unknown. Here, capitalizing on data from the Global Consortium for Chemosensory Research (GCCR) crowdsourced survey, we assessed chemosensory abilities after the resolution of respiratory symptoms in participants diagnosed with COVID-19 during the first wave of the pandemic in Italy. This analysis led to the identification of two patterns of chemosensory recovery, limited (partial) and substantial, which were found to be associated with differential age, degrees of chemosensory loss, and regional patterns. Uncovering the self-reported phenomenology of recovery from smell, taste, and chemesthetic disorders is the first, yet essential step, to provide healthcare professionals with the tools to take purposeful and targeted action to address chemosensory disorders and its severe discomfort. Cold Spring Harbor Laboratory 2021-03-26 /pmc/articles/PMC8010774/ /pubmed/33791742 http://dx.doi.org/10.1101/2021.03.25.21254253 Text en https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
spellingShingle Article
Cecchetto, Cinzia
Di Pizio, Antonella
Genovese, Federica
Calcinoni, Orietta
Macchi, Alberto
Dunkel, Andreas
Ohla, Kathrin
Spinelli, Sara
Farruggia, Michael C.
Joseph, Paule V.
Menini, Anna
Cantone, Elena
Dinnella, Caterina
Cecchini, Maria Paola
D’Errico, Anna
Mucignat-Caretta, Carla
Parma, Valentina
Dibattista, Michele
From loss to recovery: how to effectively assess chemosensory impairments during COVID-19 pandemic
title From loss to recovery: how to effectively assess chemosensory impairments during COVID-19 pandemic
title_full From loss to recovery: how to effectively assess chemosensory impairments during COVID-19 pandemic
title_fullStr From loss to recovery: how to effectively assess chemosensory impairments during COVID-19 pandemic
title_full_unstemmed From loss to recovery: how to effectively assess chemosensory impairments during COVID-19 pandemic
title_short From loss to recovery: how to effectively assess chemosensory impairments during COVID-19 pandemic
title_sort from loss to recovery: how to effectively assess chemosensory impairments during covid-19 pandemic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010774/
https://www.ncbi.nlm.nih.gov/pubmed/33791742
http://dx.doi.org/10.1101/2021.03.25.21254253
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