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Vitamin D Status: Can It Affect the Risk of Infection and the Severity of COVID-19 Symptoms?

PURPOSE OF REVIEW: In the midst of the COVID-19 pandemic, several academic studies have emerged that explore the importance of vitamin D in the development of the SARS-CoV2 infection. The basis of this interest comes from the established effect vitamin D status has on other acute respiratory infecti...

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Autores principales: Paiz, Nicole, Alonso, Paula, Portillo, Ana Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010782/
https://www.ncbi.nlm.nih.gov/pubmed/33816060
http://dx.doi.org/10.1007/s40475-021-00236-3
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author Paiz, Nicole
Alonso, Paula
Portillo, Ana Luisa
author_facet Paiz, Nicole
Alonso, Paula
Portillo, Ana Luisa
author_sort Paiz, Nicole
collection PubMed
description PURPOSE OF REVIEW: In the midst of the COVID-19 pandemic, several academic studies have emerged that explore the importance of vitamin D in the development of the SARS-CoV2 infection. The basis of this interest comes from the established effect vitamin D status has on other acute respiratory infections, such as influenza. This article aims to determine the role and effect of vitamin D serum concentration in the prevalence and severity of COVID-19. RECENT FINDINGS: Several observational studies have demonstrated that suboptimal levels of vitamin D serum concentrations can significantly increase the risk of developing COVID-19 and lead to a more severe symptomatology. One study suggests, however, that supplementation of vitamin D could potentially increase the incidence of mortality in COVID-19 patients. SUMMARY: Vitamin D status could have an influential role in the development and progression of SARS-CoV2 infection. Further studies are warranted to understand fully the veracity and the extent of this association.
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spelling pubmed-80107822021-03-31 Vitamin D Status: Can It Affect the Risk of Infection and the Severity of COVID-19 Symptoms? Paiz, Nicole Alonso, Paula Portillo, Ana Luisa Curr Trop Med Rep Metabolism in Tropical Medicine (K Schlosser-Montes, Section Editor) PURPOSE OF REVIEW: In the midst of the COVID-19 pandemic, several academic studies have emerged that explore the importance of vitamin D in the development of the SARS-CoV2 infection. The basis of this interest comes from the established effect vitamin D status has on other acute respiratory infections, such as influenza. This article aims to determine the role and effect of vitamin D serum concentration in the prevalence and severity of COVID-19. RECENT FINDINGS: Several observational studies have demonstrated that suboptimal levels of vitamin D serum concentrations can significantly increase the risk of developing COVID-19 and lead to a more severe symptomatology. One study suggests, however, that supplementation of vitamin D could potentially increase the incidence of mortality in COVID-19 patients. SUMMARY: Vitamin D status could have an influential role in the development and progression of SARS-CoV2 infection. Further studies are warranted to understand fully the veracity and the extent of this association. Springer International Publishing 2021-03-31 2021 /pmc/articles/PMC8010782/ /pubmed/33816060 http://dx.doi.org/10.1007/s40475-021-00236-3 Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Metabolism in Tropical Medicine (K Schlosser-Montes, Section Editor)
Paiz, Nicole
Alonso, Paula
Portillo, Ana Luisa
Vitamin D Status: Can It Affect the Risk of Infection and the Severity of COVID-19 Symptoms?
title Vitamin D Status: Can It Affect the Risk of Infection and the Severity of COVID-19 Symptoms?
title_full Vitamin D Status: Can It Affect the Risk of Infection and the Severity of COVID-19 Symptoms?
title_fullStr Vitamin D Status: Can It Affect the Risk of Infection and the Severity of COVID-19 Symptoms?
title_full_unstemmed Vitamin D Status: Can It Affect the Risk of Infection and the Severity of COVID-19 Symptoms?
title_short Vitamin D Status: Can It Affect the Risk of Infection and the Severity of COVID-19 Symptoms?
title_sort vitamin d status: can it affect the risk of infection and the severity of covid-19 symptoms?
topic Metabolism in Tropical Medicine (K Schlosser-Montes, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010782/
https://www.ncbi.nlm.nih.gov/pubmed/33816060
http://dx.doi.org/10.1007/s40475-021-00236-3
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