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Study on Relationships of Tumor Status and Gene Polymorphism With Blood Concentration of MTX and Toxicities in 63 Pediatric Mature B Cell Lymphoma in Chinese Population

OBJECTIVE: This study investigated the relationships of tumor status (stage, renal involvement, bone marrow status, bulky disease, liver function), tumor gene polymorphism, and methotrexate (MTX) dosage (stratified by treatment group) with blood MTX levels and adverse reactions (ADR). METHODS: We re...

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Detalles Bibliográficos
Autores principales: Huang, Shuang, Jin, Lin, Yang, Jing, Duan, Long Yan, Zhang, Meng, Zhou, Ju Chun, Zhang, Hong Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010844/
https://www.ncbi.nlm.nih.gov/pubmed/33752528
http://dx.doi.org/10.1177/1533033821995288