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Nomenclature and clinical phenotypes of atopic dermatitis

Atopic dermatitis is a heterogeneous disease and resists classification. In this review, we discuss atopic dermatitis nomenclature and identify morphologic phenotypes, which will facilitate correct diagnoses and development of treatment strategies. We support using the term ‘atopic dermatitis’ rathe...

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Autores principales: Girolomoni, Giampiero, de Bruin-Weller, Marjolein, Aoki, Valeria, Kabashima, Kenji, Deleuran, Mette, Puig, Luis, Bansal, Ashish, Rossi, Ana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010850/
https://www.ncbi.nlm.nih.gov/pubmed/33854747
http://dx.doi.org/10.1177/20406223211002979
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author Girolomoni, Giampiero
de Bruin-Weller, Marjolein
Aoki, Valeria
Kabashima, Kenji
Deleuran, Mette
Puig, Luis
Bansal, Ashish
Rossi, Ana B.
author_facet Girolomoni, Giampiero
de Bruin-Weller, Marjolein
Aoki, Valeria
Kabashima, Kenji
Deleuran, Mette
Puig, Luis
Bansal, Ashish
Rossi, Ana B.
author_sort Girolomoni, Giampiero
collection PubMed
description Atopic dermatitis is a heterogeneous disease and resists classification. In this review, we discuss atopic dermatitis nomenclature and identify morphologic phenotypes, which will facilitate correct diagnoses and development of treatment strategies. We support using the term ‘atopic dermatitis’ rather than eczema, because it describes the allergic background and inflammation (‘itis’) as drivers of the disease. Atopic dermatitis has many morphologic manifestations that vary by topographic area affected, age, or race and require consideration in differential diagnosis. Different phenotypes based on morphology and topographic location, ethnicity, and age are discussed. A better-defined phenotype identification for atopic dermatitis will facilitate earlier and correct diagnosis of this complex condition and inform selection of the most appropriate treatment choice in an era in which targeted therapies may generate more individualized patient care.
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spelling pubmed-80108502021-04-13 Nomenclature and clinical phenotypes of atopic dermatitis Girolomoni, Giampiero de Bruin-Weller, Marjolein Aoki, Valeria Kabashima, Kenji Deleuran, Mette Puig, Luis Bansal, Ashish Rossi, Ana B. Ther Adv Chronic Dis Atopic Dermatitis Atopic dermatitis is a heterogeneous disease and resists classification. In this review, we discuss atopic dermatitis nomenclature and identify morphologic phenotypes, which will facilitate correct diagnoses and development of treatment strategies. We support using the term ‘atopic dermatitis’ rather than eczema, because it describes the allergic background and inflammation (‘itis’) as drivers of the disease. Atopic dermatitis has many morphologic manifestations that vary by topographic area affected, age, or race and require consideration in differential diagnosis. Different phenotypes based on morphology and topographic location, ethnicity, and age are discussed. A better-defined phenotype identification for atopic dermatitis will facilitate earlier and correct diagnosis of this complex condition and inform selection of the most appropriate treatment choice in an era in which targeted therapies may generate more individualized patient care. SAGE Publications 2021-03-26 /pmc/articles/PMC8010850/ /pubmed/33854747 http://dx.doi.org/10.1177/20406223211002979 Text en © The Author(s), 2021 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Atopic Dermatitis
Girolomoni, Giampiero
de Bruin-Weller, Marjolein
Aoki, Valeria
Kabashima, Kenji
Deleuran, Mette
Puig, Luis
Bansal, Ashish
Rossi, Ana B.
Nomenclature and clinical phenotypes of atopic dermatitis
title Nomenclature and clinical phenotypes of atopic dermatitis
title_full Nomenclature and clinical phenotypes of atopic dermatitis
title_fullStr Nomenclature and clinical phenotypes of atopic dermatitis
title_full_unstemmed Nomenclature and clinical phenotypes of atopic dermatitis
title_short Nomenclature and clinical phenotypes of atopic dermatitis
title_sort nomenclature and clinical phenotypes of atopic dermatitis
topic Atopic Dermatitis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010850/
https://www.ncbi.nlm.nih.gov/pubmed/33854747
http://dx.doi.org/10.1177/20406223211002979
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