A case of hand urticaria, lip angioedema, and oropharyngeal pruritus induced by Japanese radish through IgE-mediated immediate allergic reaction

BACKGROUND: Although Japanese radish (Raphanus sativus L.) is a common Japanese ingredient, there are few reports of IgE-mediated immediate food allergy caused by Japanese radish. CASE PRESENTATION: A 48-year-old woman developed urticarial lesions on her hands after grating Japanese radish and also...

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Autores principales: Abe, Sumiko, Ito, Jun, Harada, Sonoko, Sasano, Hitoshi, Ueda, Shoko, Sandhu, Yuuki, Takeshige, Tomohito, Katsura, Yoko, Harada, Norihiro, Takahashi, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010957/
https://www.ncbi.nlm.nih.gov/pubmed/33789748
http://dx.doi.org/10.1186/s13223-021-00538-1
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author Abe, Sumiko
Ito, Jun
Harada, Sonoko
Sasano, Hitoshi
Ueda, Shoko
Sandhu, Yuuki
Takeshige, Tomohito
Katsura, Yoko
Harada, Norihiro
Takahashi, Kazuhisa
author_facet Abe, Sumiko
Ito, Jun
Harada, Sonoko
Sasano, Hitoshi
Ueda, Shoko
Sandhu, Yuuki
Takeshige, Tomohito
Katsura, Yoko
Harada, Norihiro
Takahashi, Kazuhisa
author_sort Abe, Sumiko
collection PubMed
description BACKGROUND: Although Japanese radish (Raphanus sativus L.) is a common Japanese ingredient, there are few reports of IgE-mediated immediate food allergy caused by Japanese radish. CASE PRESENTATION: A 48-year-old woman developed urticarial lesions on her hands after grating Japanese radish and also developed lip edema and oral itching when she ate a salad composed of raw Japanese radishes. Skin prick testing was positive to extract of grated Japanese radish. Moreover, immunoblotting analysis showed IgE reactivity in the patient’s serum to a single band at the 18 kDa in grated Japanese radish, suggesting that the heat-labile 18 kDa protein of raw Japanese radish may be a radish-specific antigen. CONCLUSIONS: To the best of our knowledge, this is the first case report of a patient with hand urticaria, lip angioedema, and oropharyngeal pruritus to raw Japanese radish through IgE-mediated immediate allergic reaction.
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spelling pubmed-80109572021-03-31 A case of hand urticaria, lip angioedema, and oropharyngeal pruritus induced by Japanese radish through IgE-mediated immediate allergic reaction Abe, Sumiko Ito, Jun Harada, Sonoko Sasano, Hitoshi Ueda, Shoko Sandhu, Yuuki Takeshige, Tomohito Katsura, Yoko Harada, Norihiro Takahashi, Kazuhisa Allergy Asthma Clin Immunol Case Report BACKGROUND: Although Japanese radish (Raphanus sativus L.) is a common Japanese ingredient, there are few reports of IgE-mediated immediate food allergy caused by Japanese radish. CASE PRESENTATION: A 48-year-old woman developed urticarial lesions on her hands after grating Japanese radish and also developed lip edema and oral itching when she ate a salad composed of raw Japanese radishes. Skin prick testing was positive to extract of grated Japanese radish. Moreover, immunoblotting analysis showed IgE reactivity in the patient’s serum to a single band at the 18 kDa in grated Japanese radish, suggesting that the heat-labile 18 kDa protein of raw Japanese radish may be a radish-specific antigen. CONCLUSIONS: To the best of our knowledge, this is the first case report of a patient with hand urticaria, lip angioedema, and oropharyngeal pruritus to raw Japanese radish through IgE-mediated immediate allergic reaction. BioMed Central 2021-03-31 /pmc/articles/PMC8010957/ /pubmed/33789748 http://dx.doi.org/10.1186/s13223-021-00538-1 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Abe, Sumiko
Ito, Jun
Harada, Sonoko
Sasano, Hitoshi
Ueda, Shoko
Sandhu, Yuuki
Takeshige, Tomohito
Katsura, Yoko
Harada, Norihiro
Takahashi, Kazuhisa
A case of hand urticaria, lip angioedema, and oropharyngeal pruritus induced by Japanese radish through IgE-mediated immediate allergic reaction
title A case of hand urticaria, lip angioedema, and oropharyngeal pruritus induced by Japanese radish through IgE-mediated immediate allergic reaction
title_full A case of hand urticaria, lip angioedema, and oropharyngeal pruritus induced by Japanese radish through IgE-mediated immediate allergic reaction
title_fullStr A case of hand urticaria, lip angioedema, and oropharyngeal pruritus induced by Japanese radish through IgE-mediated immediate allergic reaction
title_full_unstemmed A case of hand urticaria, lip angioedema, and oropharyngeal pruritus induced by Japanese radish through IgE-mediated immediate allergic reaction
title_short A case of hand urticaria, lip angioedema, and oropharyngeal pruritus induced by Japanese radish through IgE-mediated immediate allergic reaction
title_sort case of hand urticaria, lip angioedema, and oropharyngeal pruritus induced by japanese radish through ige-mediated immediate allergic reaction
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010957/
https://www.ncbi.nlm.nih.gov/pubmed/33789748
http://dx.doi.org/10.1186/s13223-021-00538-1
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