Randomized and dose-escalation trials of recombinant human serum albumin /granulocyte colony-stimulating factor in patients with breast cancer receiving anthracycline-containing chemotherapy

BACKGROUND: To evaluate the efficacy and safety of recombinant human serum albumin /granulocyte colony-stimulating factor (rHSA/G-CSF) in breast cancer following receipt of cytotoxic agents. METHODS: The phase 1b trial assessed the pharmacokinetics, pharmacodynamics, and safety of dose-escalation, r...

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Detalles Bibliográficos
Autores principales: Chen, Shanshan, Han, Yiqun, Ouyang, Quchang, Lu, Jianguo, Zhang, Qingyuan, Yang, Shun’e, Wang, Jingfen, Huang, Haixin, Liu, Hong, Shao, Zhimin, Li, Hui, Chen, Zhendong, Sun, Sanyuan, Geng, Cuizhi, Lu, Junguo, Sun, Jianwei, Wang, Jiayu, Xu, Binghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8010964/
https://www.ncbi.nlm.nih.gov/pubmed/33789616
http://dx.doi.org/10.1186/s12885-021-08093-z

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